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Oncology GlossaryBrochures

Our Oncology Glossary with the important terms explained


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Ileostomy (il-ee-OS-to-mee): An opening created by a surgeon into the ileum, part of the small intestine, from the outside of the body. An ileostomy provides a new path for waste material to leave the body after part of the intestine has been removed.

Imaging: Tests that produce pictures of areas inside the body.

Immune system (im-YOON): The complex group of organs and cells that defends the body against infection or disease.

Immunodeficiency: A lowering of the body's ability to fight off infection and disease.

Immunology: A science that deals with the study of the body's immune system.

Immunosuppression: The use of drugs or techniques to suppress or interfere with the body's immune system and its ability to fight infections or disease. Immunosuppression may be deliberate, such as in preparation for bone marrow or other organ transplantation to prevent rejection by the host of the donor tissue, or incidental, such as often results from chemotherapy for the treatment of cancer.

Immunotherapy (IM-yoo-no-THER-a-pee): Treatment that uses the body's natural defenses to fight cancer. Also called biological therapy.

Implant (or internal) radiation: Internal radiation therapy that places radioactive materials in or close to the cancer.

Impotent (IM-po-tent): Inability to have an erection and/or ejaculate semen.

Incidence: The number of new cases of a disease diagnosed each year.

Incision (in-SI-zhun): A cut made in the body during surgery.

Incontinence (in-kON-ti-nens): Inability to control the flow of urine from the bladder.

Infertility: The inability to produce children.

Infiltrating cancer: See invasive cancer.

Inflammatory breast cancer: A rare type of breast cancer in which cancer cells block the lymph vessels in the skin of the breast. The breast becomes red, swollen, and warm, and the skin of the breast may appear pitted or have ridges.

Inguinal orchiectomy (IN-gwin-al or-kee-EK-to-mee): Surgery to remove the testicle through the groin.

Insulin (IN-su-lin): A hormone made by the islet cells of the pancreas. Insulin controls the amount of sugar in the blood.

Interferon (in-ter-FEER-on): A type of biological response modifier (a substance that can improve the body's natural response to disease). It stimulates the growth of certain disease-fighting blood cells in the immune system.

Interleukin (in-ter-LOO-kin): A substance used in biological therapy. Interleukins stimulate the growth and activities of certain kinds of white blood cells.

Interleukin-2 (in-ter-LOO-kin): A type of biological response modifier (a substance that can improve the body's natural response to disease). It stimulates the growth of certain blood cells in the immune system that can fight cancer. Also called IL-2.

Internal radiation (ray-dee-AY-shun): Radiation therapy that uses radioactive materials placed in or near the tumor.

Intestine (in-TES-tin): The long, tube-shaped organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.

Intraepithelial (in-tra-eh-pih-THEEL-ee-ul): Within the layer of cells that forms the surface or lining of an organ.

Intrahepatic (in-tra-hep-AT-ik): Within the liver.

Intrahepatic bile duct (in-tra-hep-AT-ik): The bile duct that passes through and drains bile from the liver.

Intraoperative radiation therapy: Radiation treatment given during surgery. Also called IORT.

Intraperitoneal chemotherapy (IN-tra-per-i-to-NEE-al): Treatment in which anticancer drugs are put directly into the abdomen through a thin tube.

Intrathecal chemotherapy (in-tra-THEE-cal KEE-mo-THER-a-pee): Chemotherapy drugs infused into the thin space between the lining of the spinal cord and brain to treat or prevent cancers in the brain and spinal cord.

Intravenous (in-tra-VEE-nus): Injected in a vein. Also called IV.

Intravenous pyelogram (in-tra-VEE-nus PIE-el-o-gram): A series of x-rays of the kidneys and bladder. The x-rays are taken after a dye that shows up on x-ray film in injected into a vein. Also called IVP.

Intravenous pyelography (om-tra-VEE-nus py-LOG-ra-fee): X-ray study of the kidneys and urinary tract. Structures are made visible by the injection of a substance that blocks x-rays. Also called IVP.

Intravesical (in-tra-VES-ih-kal): Within the bladder.

Invasion: As related to cancer, the spread of cancer cells into healthy tissue adjacent to the tumor.

Invasive cancer: Cancer that has spread beyond the layer of tissue in which it developed. Invasive breast cancer is also called infiltrating cancer or infiltrating carcinoma.

Invasive cervical cancer: Cancer that has spread from the surface of the cervix to tissue deeper in the cervix or to other parts of the body.

IORT (intraoperative radiation therapy): Radiation treatment given during surgery.

Islet cell cancer (EYE-let): Cancer arising from cells in the islets of Langerhans.

Islets of Langerhans (EYE-lets of LANG-er-hanz): Hormone-producing cells in the pancreas.

IV (intravenous) (in-tra-VEE-nus): Injected in a vein.

IVP (intravenous pyelogram) (in-tra-VEE-nus PYE-el-o-gram): X-ray study of the kidneys, uterus, and urinary tract. Structures are made visible by the injection of a substance that blocks x-rays.

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